Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride (NMA)

1. Identification

Product Identifiers

Product Name

Nadic Methyl Anhydride (NMA)

Other Names

Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride

Product Number(s)

C046

CAS Number

25134-21-8

Recommended use of the chemical and restriction on use

Company Details

Emergency Contact Details

2. Hazards Identification

Classification of the substance or mixture

Label Elements

Signal Words

None

Hazard Statement(s)

• H302 Harmful if swallowed.
• H314 Causes severe skin burns and eye damage.
• H317 May cause an allergic skin reaction.
• H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary Statement(s)

• Prevention
• P261 Avoid breathing mist or vapours.
• P264 Wash skin thoroughly after handling.
• P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
• P284 Wear respiratory protection.

Primary route(s) of entry

Human Health

Inhalation

P304 ± P340 ± P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor.

Ingestion

P301 ± P330 ± P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

Eyes

• P305 ± P351 ± P338 ± P310
• IF IN EYES: Rinse cautiously with water for several minutes.
• Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor.

Skin

P303 ± P361 ± P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.

Environment

3. Composition / Information on Ingredients

4. First Aid Measures

Ingestion

Call for a doctor immediately.

Inhalation

In case of unconsciousness place patient stably in side position for transportation.

Skin Contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.

Eye Contact

Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.

Other Information

Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident.

5. Firefighting Measures

Suitable extinguishing equipment

Fire

CO₂, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.

HAZCHEM

Not available.

Special protective equipment and precautions for fire fighters

6. Accidental Release Measures

Personal precautions, protective equipment and emergency procedures

• Advice for non-emergency personnel: Do not breathe vapours, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
• For personal protection see section 8.

Environmental precautions

Do not allow to enter sewers/ surface or ground water.

Methods and materials for containment and clean up

• Dispose contaminated material as waste according to item 13.
• Ensure adequate ventilation.

7. Handling and Storage

Precautions for safe handling

• Ensure good ventilation/exhaustion at the workplace.
• Keep away from foodstuffs, beverages and feed.
• Immediately remove all soiled and contaminated clothing.

Conditions for safe storage

• Storage conditions
• Tightly closed. Keep locked up or in an area accessible only to qualified or authorised persons.
• Moisture sensitive.
• Storage class
• Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

8. Exposure Controls / Personal Protection

Exposure Standards

Engineering controls

No information available.

Personal protective equipment

Eye and face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles

Skin protection

• Wash hands before breaks and at the end of work.
• Avoid contact with the eyes and skin.

Body protection

• Keep away from foodstuffs, beverages and feed.
• Immediately remove all soiled and contaminated clothing.

Respiratory protection

In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use self-contained respiratory protective device.

9. Physical and Chemical Properties

General information

Appearance

Liquid

Odour

Characteristic

pH

Not determined.

Vapour Pressure

Not determined.

Density

1.232 g/cm³ (10.28104 lbs/gal)

Boiling Point

Undetermined.

Melting Point

Undetermined.

Solubility

Not determined.

Specific Gravity of Density

Not applicable.

Flash Point

135 °C (275 °F)

Flammable (Explosive) Limits

Not applicable.

Ignition Temperature

Not determined.

Formula

Not available.

10. Stability and Reactivity

Reactivity

No further relevant information available.

Chemical stability

Not available.

Possibility of hazardous reactions

No dangerous reactions known.

Conditions to avoid

No further relevant information available.

Incompatible materials

No further relevant information available.

11. Toxicological Information

Acute effects

No further relevant information available.

Eye contact

Irritating effect.

Skin contact

Irritant to skin and mucous membranes.

Ingestion

No further relevant information available.

Inhalation

No further relevant information available.

Toxicity and irritation

No further relevant information available.

12. Ecological Information

Ecotoxicity

No further relevant information available.

Persistence and degradability

No further relevant information available.

Bioaccumulative potential

No further relevant information available.

Other adverse effects

Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.

13. Disposal Considerations

General information

14. Transport Information

ADG label required

HAZCHEM

Not available.

UN Number

UN2810

Proper shipping name

• DOT Toxic, liquids, organic, n.o.s. (NMA, (Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride))
• ADR 2810 TOXIC LIQUID, ORGANIC, N.O.S. (NMA, (Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride))
• IMDG, IATA TOXIC LIQUID, ORGANIC, N.O.S. (NMA, (Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride))

Transport hazard class

6.1 Toxic substances

Packing group

PG III

Environmental hazard

No information available.

Special precautions for users

• Special precautions for user Warning: Toxic substances
• Hazard identification number (Kemler code): 60
• EMS Number: F-A,S-A

Additional information

• Transport/Additional information:
• DOT · Quantity limitations On passenger aircraft/rail: 60 L
• On cargo aircraft only: 220 L
• ADR · Excepted quantities (EQ) Code: E1
• Maximum net quantity per inner packaging: 30 mL
• Maximum net quantity per outer packaging: 1000 mL
• IMDG · Limited quantities (LQ) 5L
• Excepted quantities (EQ) Code: E1
• Maximum net quantity per inner packaging: 30 mL
• Maximum net quantity per outer packaging: 1000 ml

15. Regulatory Information

Poisons Schedule Number

Substance is not listed.

Other Information

No further relevant information available.

16. Other Information

SDS preparation date

9 December 2025

Comments

• Abbreviations and acronyms:
• ADR: Accord relatif au transport international des marchandises dangereuses par route (European Agreement Concerning the International
• Carriage of Dangerous Goods by Road)
• IMDG: International Maritime Code for Dangerous Goods
• DOT: US Department of Transportation
• IATA: International Air Transport Association
• EINECS: European Inventory of Existing Commercial Chemical Substances
• CAS: Chemical Abstracts Service (division of the American Chemical Society)
• NFPA: National Fire Protection Association (USA)
• HMIS: Hazardous Materials Identification System (USA)
• PBT: Persistent, Bioaccumulative and Toxic
• vPvB: very Persistent and very Bioaccumulative
• NIOSH: National Institute for Occupational Safety
• OSHA: Occupational Safety Health
• TLV: Threshold Limit Value
• PEL: Permissible Exposure Limit
• REL: Recommended Exposure Limit
• Acute toxicity - oral 4: Acute toxicity - Category 4
• Skin corrosion 1C: Skin corrosion/irritation - Category 1C
• Eye irritation 2A: Serious eye damage/eye irritation - Category 2A
• Sensitization - respiratory 1: Respiratory sensitisation - Category 1
• Specific target organ toxicity (single exposure) 3: Specific target organ toxicity (single exposure) - Category 3

References

• EMS SDS NMA, (Methyl-5-Norbornene-2,3-Dicarboxylic Anhydride) 01/02/2025 https://www.emsdiasum.com/docs/technical/msds/19000.pdf
• Sigma-Aldrich SDS Methyl-5-norbornene-2,3-dicarboxylic anhydride 26/10/2023 https://www.sigmaaldrich.com/AU/en/sds/aldrich/235431-userType=anonymous